Timothy c. Hain, MD

645 N Michigan, Suite 410
312-274-0197
(312) 274-0197

Research Profile

• Robinson DA, Zee DS, Hain TC, Holmes AM, Rosenberg LF: Alexander's law -- its behavior and origin in the human vestibulo-ocular reflex. Ann. Neurology., 16:714-722, 1984.
• Kapoula ZA, Robinson DA, Hain TC: Motion of the eye immediately after a saccade. Experimental. Brain Research., 61:386-394, 1986.
• Hain TC, Zee DS, Mordes M: Blink-induced saccadic oscillations. Annals Neurology., 19:299-301, 1986.
• Hain TC: A model of the nystagmus induced by off-vertical axis rotation. Biological Cybernetics, 54:337-350, 1986.
• Fetter M, Hain TC, Zee DS: Influence of eye and head position on the vestibulo-ocular reflex. Experimental. Brain Research., 64:208-216, 1986.
• Lasker AG, Zee DS, Hain TC, Folstein S: Saccadic eye movements in Huntington's Disease: Initiation defects and distractibility. Neurology, 37: 364-370, 1987.
• Zee DS, Hain TC, Carl JR: Abduction nystagmus in internuclear ophthalmoplegia. Annals Neurology., 21:383-388, 1987.
• Hain TC, Fetter M, Zee DS: Head-shaking nystagmus in unilateral peripheral vestibular lesions. American J. Otolaryngology., 8:36-47, 1987.
• Kapoula Z, Hain TC, Zee DS, Robinson DA: Adaptive changes in post-saccadic drift induced by patching one eye. Vision Research, 27:1299-1307, 1987.
• Hain TC, Zee DS, Maria B: Tilt-suppression of the vestibulo-ocular reflex in patients with cerebellar lesions. Acta Otolaryngology. (Stockh), 105:13-20, 1988.
• Lasker AG, Zee DS, Hain TC, Folstein SF, Singer H: Saccades in Huntingtons disease: Slowing and dysmetria. Neurology, 38:427-431, 1988.
• Levin S, Luebke A, Hain TC, Zee DS, Robinson DA, Holzman PS: Smooth pursuit eye movements in schizophrenics: quantitative measurements with the search-coil Technique. J. Psych. Research, 22:195-206, 1988.
• Furman J, Hain TC, Paige G: Central adaptation model of the vestibulo-ocular and optokinetic systems. Biological. Cybernetics., 61:255-264, 1989.
• Tijssen M, Straathof C, Hain TC, Zee DS: Optokinetic afternystagmus in humans: normal values of amplitude, time constant and asymmetry. Annals Otology, Rhinolology, Laryngology, 98:741-746, 1989.
• Wei D, Hain TC, Proctor L: Head-shaking nystagmus: associations with canal paresis and hearing loss. Acta Otology. 108: 362-367, 1989.
• Hain TC, Luebke A: Phoria adaptation in patients with cerebellar lesions. Investigative Ophthalmology. 1990.
• Fletcher WA, Hain TC, Zee DS: Optokinetic nystagmus and afternystagmus in human beings: relationship to nonlinear processing of information about retinal slip. Experimental Brain Research, 1990.
• Hain TC, Buettner UE: Static roll and the vestibulo-ocular reflex (VOR). Experimental Brain Research. 82:463-471, 1990.
• Ashe J, Hain TC, Zee DS: Microsaccadic oscillation -- a new clinical syndrome. Brain, 114, 461-472, 1991.
• Hain TC, Zee DS: Abolition of optokinetic afternystagmus by aminoglycoside ototoxicity. Annals Otology. 100:580-583, 1991.
• Hain TC, Patel G: Slow-cumulative Eye Position to Quantify Optokinetic Afternystagmus. Annals Otology. 101:255-260, 1992.
• Zee DS, Hain, TC: Clinical Implications of Otolith-Ocular Reflexes. American Journal of Otology, 13, 152-157, 1992.
• Hanson DG, Logemann JA, Hain TC: Differential diagnosis of spasmodic dysphonia: a kinetic perspective. J. Voice 6, 3-, 1992.
• Tusa RT, Zee DS, Hain TC: Voluntary control of congenital nystagmus, Clinical Vision Sciences 7, 195-210, 1992.
• Herdman SJ, Sandusky AL, Hain TC, Zee DS, Tusa RJ: Characteristics of postural stability in patients with gentamicin toxicity. J. Vestibular Research. 4:71-80, 1994.
• Hain TC, Herdman SJ, Holliday MS, Mattox D, Zee DS, Byskosh AT: The localizing value of optokinetic afternystagmus. Annals ORL, 806-811, 1994.
• Harvey SA, Hain TC, Adamiec LC: Modified liberatory maneuver: Effective treatment for benign paroxysmal positional vertigo. Laryngoscope 104:1206-1212, 1994.
• Hain TC: Treatment of Vertigo. The Neurologist. 1: 125-133, 1995.
• Young NM, Johnson JC, Mets B, Hain TC: Cochlear implants in young children with Usher's syndrome. Annals ORL, supplement 166, 104, 9, part-II, 342-345, 1995.
• Rascol O, Hain TC, Benazet M, Clanet M, Montastruc JL: Antivertigo Medications and Drug-Induced Vertigo. Drugs 50(5):777-791, 1995.
• Young NM, Mets M, Hain TC: Early Diagnosis of Usher Syndrome in Infants and Children. Am. J. Otology, 17:1, 30-34, 1996.
• Rogers MW, Hain TC, Hanke TA, Janssen I: Effects of stimulus parameters and inertial load on the incidence of protective stepping responses in healthy human subjects. Arch Phys Med Rehabil 77:363-368, 1996.
• Peng GCY, Hain TC, Peterson BW: A dynamical model for reflex activated head movements in the horizontal plane. Biological Cybernetics, 75, 309-319, 1996.
• Ostrowski VB, Hain TC, Wiet R: Pressure Induced Ocular Torsion. Archives in Otolaryngology-Head and Neck Surgery. 1997.
• Hain TC, Ostrowski, VB. Limits of Normal for Pressure Sensitivity in the Fistula Test. Audiology and Neuro-otology 2:384-390, 1997
• Voice F0 Responses to Manipulations in Pitch Feedback, Burnett TA, Freedland MB, Larson CR, Hain TC, J. Acoustical Soc America, 103, 3153-3161, 1998
• Riggs LC, Shofner WP, Shah AR, Young MR, Hain TC, Matz GJ. Ototoxicity resulting from combined administration of metronidazole and gentamicin. Am J Otol 1999 Jul;20(4):430-4
• Hain TC, Hanna P, Rheinberger M. Mal de Debarquement Syndrome.Archives of Otolaryngology-Head Neck Surgery, 1999:125:615-620, Also see local link to Mal de Debarquement, and PDF file at Arch Otolaryngol site
• Hain TC, Fuller L, Weil L, Kotsias J. Effects of T'ai Chi on Balance. Arch Otolaryngol Head Neck Surg 1999 Nov;125(11):1191-5. Also see local link and PDF file on Arch Otolaryngol site.
• Keshner EA, Hain TC, Chen KJ. J Vestib Res 1999;9(6):423-34 Predicting control mechanisms for human head stabilization by altering the passive mechanics.
• Peng GC, Hain TC, Peterson BW. IEEE Trans Biomed Eng 1999 Nov;46(11):1269-80. Predicting vestibular, proprioceptive, and biomechanical control strategies in normal and pathological head movements.
• Hain TC, Burnett TA, Kiran S, Larson CR, Singh S, Kenney MK. Exp Brain Res 2000 Jan;130(2):133-41. Instructing subjects to make a voluntary response reveals the presence of two components to the audio-vocal reflex.
• Larson CR, Burnett TA, Kiran S, Hain TC. J Acoust Soc Am 2000 Jan;107(1):559-64. Effects of pitch-shift velocity on voice Fo responses.
• Hain TC, Helminski JO, Reis IL, Uddin K. Vibration does not improve results of the canalith repositioning procedure. Arch Otolaryngol Head Neck Surg, May 2000, 126(5) 617-22
• Fife TD, Tusa RJ, Furman JM, Zee DS, Frohman E, Baloh RW, Hain T, Goebel J, Demer J, Eviatar L. Assessment: vestibular testing techniques in adults and children: Report of the therapeutic and technology subcommittee of the American Academy of Neurology. Neurology, 2000, 55:10, 1431-1441
• Ostrowski V, Hain TC. Vectorial analysis of the Tullio's phenomenon associated with superior canal dehiscence. Otology and Neurotology, 22:61,2001
• Hain TC, Burnett TA, Larson CR, and Kiran S,. Effects of delayed auditory feedback (DAF) on the pitch-shift reflex. J. Acoustical Soc. Am 109 (5), May 2001 50.
• Larson CR, Burnett TA, Bauer JJ, Kiran S, Hain TC. Comparison of voice F0 responses to pitch-shift onset and offset conditions. J. Acoust Soc Am, 110 (6), Dec 2001, 2865-2648
• Peterson BW, Choi H, Hain T, Keshner E, Peng GC. (2001) Dynamic and kinematic strategies for head movement control. Ann N.Y.Acad Sci. 942:381-93.
• Chiu B, Hain TC. Periodic alternating nystagmus provoked by an attack of Meniere's disease. J. Neuro-ophthalmology 2002;22:107-109
• Chen KJ, Keshner EA ,Peterson BW, Hain TC, Modeling head tracking of visual targets. JVR 12, 2002, 25-33
• Mamikoglu B, Wiet RJ, Hain T, Check IJ. Increased CD4+ T cells during acute attack of Meniere's disease.Acta Otolaryngol 2002 Dec;122(8):857-60
• Hain TC, Uddin M. Pharmacological treatment of vertigo CNS Drugs 2003;17(2):85-100
• Simoneau M,. Tinker S, Hain TC, and Lee WA. Effects of predictive mechanisms on head stability during forward trunk perturbation. Exp Brain Res .148(3): 338-49. (2003).
• Hoistad DL. and Hain TC. "Central hearing loss with a bilateral inferior colliculus lesion." Audiol Neurootol 8(2): 111-3. ,2003.
• Brenner M, Hoistad D, Hain TC. Prevalence of thyroid dysfunction in Meniere's Disease. Archives of Oto HNS, 130/2 226-228 (2004)
• Squires, T.M., et al., A mathematical model for top-shelf vertigo: the role of sedimenting otoconia in BPPV. J Biomech, 2004. 37(8): p. 1137-46.
• Yacovino DA, Hain TC. (Article in Spanish) [Neck vibration: Usefulness in neurotology] Rev Neurol. 2004 Jun 1-15;38(11):1061-6.
• Furman, J.M. and T.C. Hain, "Do try this at home": self-treatment of BPPV. Neurology, 2004. 63(1): p. 8-9.
• Yi Xu, Charles Larson, Jay Bauer, Timothy Hain "Compensation for pitch-shifted auditory feedback during the production of Mandarin tone sequences. JASA, 2004.
• Yacovino, D. A. and T. C. Hain. "[The pharmacology of vestibular disorders]." Rev Neurol39(4): 381-7. (2004)
• Moon I, Hain TC Delayed Quick Spins following Vestibular Nerve Section Respond to Anticonvulsant Medication. Otol Neurotol 26:82-85 (2005)
• Hain, T. C., T. M. Squires and H. A. Stone (2005). "Clinical implications of a mathematical model of benign paroxysmal positional vertigo." Ann N Y Acad Sci1039: 384-94.
• Helminski, J. O., I. Janssen, D. Kotaspouikis, Hain TC. (2005). "Strategies to prevent recurrence of benign paroxysmal positional vertigo." Arch Otolaryngol Head Neck Surg 131(4): 344-8.
• Gurses S, Dhaher Y, Hain TC, et al. (2005). "Perturbation parameters associated with nonlinear responses of the head at small amplitudes." Chaos 15(2): 2005.
• Bauer J, Mittal J, Larson CR, Hain TC. Vocal responses to unanticipated perturbations in voice loudness feedback: An automatic mechanism for stabilizing voice amplitude. JASA April 2006 119(4) 2363-2371
• Hain, TC. Head-shaking Nystagmus and New Technology (Editorial). Neurology. 68: 17, 1333-1334 (2007)
• Keshner, E. A., J. Streepey, et al. (2007). "Pairing virtual reality with dynamic posturography serves to differentiate between patients experiencing visual vertigo." J Neuroengineering Rehabil 4(1): 24.
• Larson, C. R., J. Sun, et al. (2007). "Effects of simultaneous perturbations of voice pitch and loudness feedback on voice F0 and amplitude control." J Acoust Soc Am 121(5 Pt1): 2862-72.
• Helminski JO, Hain TC. Evaluation and Treatment of Benign Paroxysmal Positional Vertigo. Annals of Long-Term Care: Clinical Care and Aging 2007;15[6]:33-39)
• Unsteady Influences. Hain TC, Ostrowski T. Advances in Rehabilitation, 11/2007 (Menieres's disease)