News & Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Ken & Ruth Davee Department of Neurology.
Imbalanced activation of cells and previously unknown neural connections may be responsible for some motor symptoms in Parkinson’s disease and similar neurodegenerative conditions, according to two recent studies.
More than 350 participants attended the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease’s virtual PPA Conference, which featured keynote speakers and group support sessions focused on Primary Progressive Aphasia.
Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis, according to a recent study.
Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
Northwestern Medicine scientists have discovered a conformational “switch” that determines the function of the SNARE protein Ykt6, with implications for synucleinopathies, according to a recent study.
Northwestern and Lurie Children’s Hospital investigators have been approved for a $4 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to study Lennox-Gastaut Syndrome.
An experimental spherical nucleic acid drug developed by Northwestern scientists was able to penetrate the blood-brain barrier and trigger the death of glioblastoma cells.
Northwestern Medicine scientists discovered mutations in a scaffolding protein contributes to dystonia, an incurable movement disorder.
Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
For the first time, Northwestern Medicine scientists have characterized how a genetic mutation associated with pediatric epilepsy affects neuron activity.
Northwestern Medicine scientists have uncovered a neural circuit that drives fear-induced suppression of feeding, according to a study published in Neuron.
For the first time, Northwestern Medicine scientists have uncovered the complex logic that determines how cochlear cells are connected to the brain during neurodevelopment, according to a recent study.
An experimental drug called ezogabine reduced spinal neuron excitability in patients with ALS, according to a recent study.
Homer1, a protein that’s important for neural plasticity and learning, is part of a large network of proteins in the brain that help ensure new connections are wired correctly, according to a new study.
The strength of neuron-to-neuron connections does not govern the spread of Parkinson’s disease in the brain, according to a recent study.
Second-year medical students Jeff Clark, Nathan Shlobin, and Steven Hoffman are the co-authors of a first of its kind study, which found that more than 80 percent of patients hospitalized with COVID-19 experienced neurological manifestations.
Mutations in PCM1, a gene involved in the formation of cilia, were linked with schizophrenia in a variety of animal models and in human genome analysis, according to a recent study.
Northwestern scientists have determined how two protein mutations responsible for the impaired motor function in Parkinson’s disease independently disrupt neuron activity.
Feinberg investigators are breaking down the mechanisms of aging and designing solutions to extend healthy living.
The 10th Annual Les Turner Symposium on ALS — the first held virtually — featured scientific presentations, updates on innovative clinical trials and a question-and-answer session for patients and caretakers.
A cell-surface protein is essential for proper microcircuit function in the brain, according to a study published in Nature Communications.
Astrocytes may play a protective role in Parkinson’s disease, slowing alpha-synuclein accumulation in neurons, according to a study published in The Journal of Neuroscience.
A new study provides a missing link between inflammation and protein deposits that contribute to Alzheimer’s disease.
A recent Northwestern Medicine study may improve the understanding of mitochondrial dysfunction and its impact on the development of neurological diseases.
A novel deep brain stimulation device significantly improved quality of life for patients with advanced Parkinson’s disease while also reducing common physical side effects from medication, according to findings published in The Lancet Neurology.
A Northwestern Medicine scientist and collaborators have used an AI-enhanced precision medicine approach to combine multiple views of human brain development as they seek to provide a roadmap for what causes subtypes of autism spectrum disorder.
Inter-organelle contacts drive calcium transfer from lysosomes to mitochondria, findings that lay out a possible therapeutic blueprint for neurological disorders.
Northwestern Medicine investigators have discovered that a specific protein known for its role in cell division also impacts the direction of intracellular transport in neurons.
Neurons in the olfactory cortex coordinate to boost the sense of smell when anticipating an odor, according to a Northwestern Medicine study.
African Americans who were exposed to segregation in their neighborhoods during young adulthood are more likely to have poor cognitive performance as early as midlife.