News & Announcements

Northwestern Medicine investigators led by Amy Heimberger, MD, PhD, have discovered a new mechanism in which cancer-associated fibroblasts are associated with tumor grade and mediate immune suppression in glioma tumors.

A new study has found the immune system in the blood of Alzheimer’s patients is epigenetically altered, and many of these altered genes are the same ones that increase an individual’s risk for Alzheimer’s.

A new Northwestern Medicine study has identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains.

An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.

Insertable cardiac monitors detected a higher incidence of atrial fibrillation in patients with prior ischemic stroke over a three-year period than standard medical monitoring methods, according to results published in JAMA Neurology, based on long-term findings from the Northwestern Medicine-led STROKE AF clinical trial.

A pair of recent studies from the laboratory of Evangelos Kiskinis, PhD, have uncovered novel cellular mechanisms that are involved in two types of genetic ALS, providing support for future development of targeted therapies to treat the disease.

A new Northwestern Medicine study has demonstrated how differences in neural activity within the brain’s olfactory and orbital cortices cause people to perceive the same odors differently, according to findings published in Nature Neuroscience.

An experimental drug targeting a genetic variant linked to Parkinson’s disease had no effect on patients, according to the results of a new clinical trial published in The Lancet Neurology.

A new Northwestern University-led study published in Nature Neuroscience has discovered that dopamine neurons are more diverse than previously thought, opening new research directions for further understanding and potentially even treating Parkinson’s disease.

A recent Northwestern Medicine study has revealed that the brain’s temporal pole has critical functions in word comprehension, face recognition and the regulation of behavior.

Northwestern Medicine scientists have discovered how octopamine, the major “fight-or-flight” neurotransmitter in invertebrates, communicates with other cells to prevent cell death in mammalian brains, according to a study published in the Proceedings of the National Academy of Sciences.