Stroke & Neurocritical Care Trials
As part of an academic medical center, the Division of Stroke & Neurocritical Care at Northwestern University Feinberg School of Medicine aims to improve human health through scientific research. Clinical trials test or study drugs, surgical procedures, medical devices or interventions with human subjects. They look to determine their safety and effectiveness in relation to treating specific diseases. Clinical trials are part of clinical research and are at the heart of all medical advances.
The following searchable list includes all the stroke and neurocritical care clinical trials currently looking for participants.
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cIRB: AtRial Cardiopathy and Antithrombotic Drugs In prevention After Crypotgenic Stroke ARCADIA is a multicenter, biomarker-driven, randomized, double-blind, active-control, phase 3 clinical trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of u… ARCADIA is a multicenter, biomarker-driven, randomized, double-blind, active-control, phase 3 clinical trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of unknown cause. Eleven hundred subjects will be recruited over 2.5 years at 120 sites in the NINDS StrokeNet consortium. Subjects will be followed for a minimum of 1.5 years and a maximum of 4 years for the primary efficacy outcome of recurrent stroke and the primary safety outcomes of symptomatic intracranial hemorrhage and major hemorrhage other than intracranial hemorrhage. Inclusion Criteria: 1) Age ≥ 45 years. 2) Clinical diagnosis of ischemic stroke + brain imaging to rule out hemorrhagic stroke. 3) Modified Rankin Scale (MRS) score ≤ 4. 4) Ability to be randomized within 3 to 120 days after stroke onset. 5) ESUS, defined as all of the following: Stroke detected by CT or MRI that is not lacunar. Lacunar is defined as a subcortical (this includes pons and midbrain) infarct in the distribution of the small, penetrating cerebral arteries whose largest dimension is ≤1.5 cm on CT or ≤2.0 cm on MRI diffusion images/ NCT03192215 STU00206251 |