Stroke & Vascular Neurology Trials

As part of an academic medical center, the Division of Stroke & Vascular Neurology at Northwestern University Feinberg School of Medicine aims to improve human health through scientific research. Clinical trials test or study drugs, surgical procedures, medical devices or interventions with human subjects. They look to determine their safety and effectiveness in relation to treating specific diseases. Clinical trials are part of clinical research and are at the heart of all medical advances.

The following searchable list includes all the stroke clinical trials currently looking for participants.

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Trials
MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2) (Protocol #: B01-04) A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem®, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours.… A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem®, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours. Eligibility Criteria Primary Inclusion Criteria: Male or female subjects ≥18 years of age Clinical diagnosis of ischemic stroke involving cerebral cortex Onset of stroke symptoms must have occurred 18 to 36 hours prior to the planned start of administration of the investigational product Occurrence of a moderate to moderately severe stroke with a persistent neurologic deficit documented by a NIHSS score of 8 to 20 (inclusive) that does not change by ≥4 points during the initial screening period A mRS score of 0 or 1 prior to the onset of symptoms of the current stroke Primary Exclusion Criteria: Presence of a lacunar or a brainstem infarct Comatose state Brain hemorrhage Major neurological event such as stroke or clinically significant head trauma within 6 months of enrollment into the study Principal Investigator Batra, Ayush Location(s) Map it 201 E. Huron St. Chicago, IL Map it 259 E. Erie St. Lavin Pavillion, Suite 19 100 Chicago, IL ClinicalTrials.gov IdentifierNCT03545607IRB number STU00209969 More Info Keywords stroke stem cell multistem stroke treatment stroke recovery ischemic stroke Email Garcia-Canga, Blas Ignacio Phone +1 312 503 0492 Copy Study URL to Clipboard Copy

Trials

MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2) (Protocol #: B01-04)

A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem®, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours.…

Eligibility Criteria

Primary Inclusion Criteria:

Male or female subjects ≥18 years of age
Clinical diagnosis of ischemic stroke involving cerebral cortex
Onset of stroke symptoms must have occurred 18 to 36 hours prior to the planned start of administration of the investigational product
Occurrence of a moderate to moderately severe stroke with a persistent neurologic deficit documented by a NIHSS score of 8 to 20 (inclusive) that does not change by ≥4 points during the initial screening period
A mRS score of 0 or 1 prior to the onset of symptoms of the current stroke

Primary Exclusion Criteria:

Presence of a lacunar or a brainstem infarct
Comatose state
Brain hemorrhage
Major neurological event such as stroke or clinically significant head trauma within 6 months of enrollment into the study

Principal Investigator

Batra, Ayush

Location(s)

Map it 201 E. Huron St.
Chicago, IL
Map it 259 E. Erie St. Lavin Pavillion, Suite 19 100
Chicago, IL

ClinicalTrials.gov IdentifierNCT03545607IRB number STU00209969

More Info

Keywords stroke stem cell multistem stroke treatment stroke recovery ischemic stroke

Email Garcia-Canga, Blas Ignacio Phone +1 312 503 0492

Copy Study URL to Clipboard Copy